POST-TRAUMATIC EROSIONS OF ARTICULAR CARTILAGE

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Post-traumatic Erosions of Articular Cartilage.

Erosions of articular cartilage are often seen in the knee joint in association with certain internal derangements such as meniscus tears or after recurrent subluxation of the patella (Helfet 1959, Smillie 1962). Also a number of studies have appeared on the pathology of articular cartilage after injury, both in man (Landells 1957) and in experimental animals (Barnett 1956. Tallqvist 1962, Meac...

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Pathology of the Calcified Zone of Articular Cartilage in Post-Traumatic Osteoarthritis in Rat Knees

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Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis

OBJECTIVE Identify gene changes in articular cartilage of the medial tibial plateau (MTP) at 2, 4 and 8 weeks after destabilisation of the medial meniscus (DMM) in mice. Compare our data with previously published datasets to ascertain dysregulated pathways and genes in osteoarthritis (OA). DESIGN RNA was extracted from the ipsilateral and contralateral MTP cartilage, amplified, labelled and h...

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Articular cartilage and changes in Arthritis: Collagen of articular cartilage

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Collagen of articular cartilage

The extracellular framework and two-thirds of the dry mass of adult articular cartilage are polymeric collagen. Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix. In developing cartilage, the core fibrillar network is a cross-linked copolymer of collagens II, IX and XI. The functions of collagens I...

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ژورنال

عنوان ژورنال: The Journal of Bone and Joint Surgery. British volume

سال: 1964

ISSN: 0301-620X,2044-5377

DOI: 10.1302/0301-620x.46b3.530